I've just caught up with The Knick, and yes, it is head and shoulders above the other new series. The money they've poured into that show! The attention to detail is astonishing, both in the 1900 settings and the way medicine was practiced at the time. (Such as surgeons operating without surgical masks or gloves, which hadn't been invented yet.) Soderbergh and Owen are a winning combination. This is quality TV.
It's interesting, though, that it's one of two new shows featuring a drug-addicted doctor as the protagonist. The other is Rush, nowhere near the same class as The Knick.